The US and other countries restrict who can work with certain germs, but it might be possible to build some viruses from their genes. A number of firms supply DNA sequences to order. A 2005 investigation by New Scientist raised alarms when it found that only five out of 12 of these firms in North America and Europe always screened orders for sequences that might be used in bioweapons.
The US now wants firms to verify a customer's identity and make sure they are not on a list of banned buyers. It also wants them to screen orders for sequences that are unique to Select Agents, a list of microbes the US deems dangerous.
However, scientists commenting on the draft rules earlier this year fear that sequences from microbes other than Select Agents might also be dangerous. The US Department of Health says not enough is known about them to say which ones should arouse a firm's suspicions. Other potential weaknesses include the fact that the rules are voluntary, and that much custom DNA is made outside the US."
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